Molecular characterisation of major histocompatibility complex (MHC) peptides
Antigen-antibody epitope mapping
Antibody sequencing
Cytokine profiling
Providing advanced insights with mass spectrometry
Biomedical proteomics is a powerful tool for the development of targeted therapeutics, with applications in many areas of drug discovery and development. At Krems Bioanalytics, we specialise in several areas of biomedical proteomics, including characterisation of the human immune response, plasma proteomics, protein interactions in macromolecular complexes, and pharmacokinetic (PK) testing of large molecules.
By using advanced mass spectrometry techniques, we can identify and quantify specific proteins and post-translational modifications involved in the immune response, providing insights into the pathophysiology of diseases and potential therapeutic targets. Our plasma proteomics services can also help to identify disease biomarkers and improve diagnostic accuracy.
Identifying therapeutic targets and optimising drug design
Protein interactions in macromolecular complexes are critical for many biological processes, and our expertise in this area can help to identify new therapeutic targets and optimise drug design. Our PK testing services can also help to assess the pharmacokinetics of large molecules, including proteins and antibodies, which is essential for predicting clinical efficacy and safety.
Whether you are developing a new drug or need help with a specific proteomics project, our team of experts is here to help. Contact us today to learn more about our biomedical proteomics services and how we can support your drug development programmes.